In the body it appears after the Menopause. Estrone fromed from the estradiol and its precursor is estradiol.
Estradiol:
Both male and female can produce the hormone estradiol, it appears during reproduction period. Estradiol with the combination of ovarian hormones activates the enzyme deoxyribonuclease enzyme within the cell.
Estriol:
Estriol is the weakest form of estrogen and it is very important during pregnancy because it helps the growth of uterus and prepares the body for parturition. After the parturition the level of estriol is getting low. This estriol is produced from the estrogen . During pregnancy the placenta releases the hormone estriol.
Estrogen Effects and Functions on Uterus
The mucous membrane surrounds and protects the uterus. The function of estrogen is to enhance and maintain the layer mucous membrane within the uterus there is a secretion called uterine mucus secretion. Estrogen regulates the secretion and also used in the thickening of the uterus. Every individual having different level of estrogen. Especially, during menstruation. Most of the women can realize the mood changes and irritation in that situation of menstrual cycle. Some of the factors which affect the estrogen level in pregnancy, lactation, menstruation, obesity, diet, exercise, primary ovarian insufficiency, and tumors. The young women uterus is sensible to receive estrogen, but the adult women uterus does not receive the estrogen because of tissue degeneration. Some types of estrogens are more active than others because of the arrangements and number of atom modification in the estrogen molecule. This modification continues until the reproductive cycle ends. As a steroid hormone the estrogens binds to the receptors in the cell through it signals the biological changes occurs in the body. All estrogen molecules are similar in their chemical structure, but they are differ in the function within the uterus. The reduced estrogen production also causes vaginal dryness. And, also in the conditions include hypogonadism and polycystic ovarian syndrome.
Uterine Contraction
Adequate uterine contractility results the successful embryo implantation through the transport of semen and gametes. And, inadequate contractility results ectopic pregnancies, miscarriages, retrograde, bleeding and endometriosis. In uterine the contraction waves showing higher frequency in periovulatory phase. Whereas the contraction waves showing lower frequency in other phases. In the embryo implantation the estrogen allows the free transport of semen and gametes. Estrogen perfusion results the high peristaltic waves that starts from the isthmus uteri and towards the corpus uteri.
Estrogen Imbalance
Estrogen imbalance affects the menstrual cycle. Lighter or heavier bleeding during the menstrual period. The symptoms like hot flashes and night sweats. Within the uterus it produces the tumor like lumps which is noncancerous. In women during pregnancy the level of estrogen increases. It prevents other eggs from maturation and also helps in lactation by developing the breast. Oxytocin is released from the pituitary gland under the guidance of estrogen at the end stage of childbirth. Relaxin is released from the ovaries it relaxes the pelvic ligaments for easier parturition without complication.
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